The microblog "Twitter" relies on the paradigm of Publish/Subscribe middlewares I've researched before. The only difference is that subscribers can also reply to publishers.
In comparison to other existing messaging systems, Twitter appears to be a truly asynchronous messaging mechanism. Unlike MSN, enabling asynchrony at infrastructure level but, at user level, most MSN users don't behave asynchronously during conversion resulting in anxiety of getting immediate replies.
The current hype of Twitter results in my own one at http://twitter.com/teparit
Someone said Facebook and Twitter are becoming "social utility" (สาธารณูปโภคเชิงสังคม)... Probably like Coffee, a "working utility".